Constipation
Adult
Approach
Red flags for colon cancer?
Sudden onset, severe constipation: FOBT and refer for colonoscopy if positive
Painless colorectal bleeding
Explore alternative diagnoses, e.g. anal fissure, hemorrhoids, anoreceptive intercourse
Refer for colonoscopy if age > 30 years and any of the following are true:
No alternative explanation
Persistent bleeding despite adequate treatment of alternative diagnosis
Review risk factors and consider
Discontinuing offending medications
Obtaining HbA1c, TSH, UDS
Treatment
Trial of laxatives
Laxatives ineffective
Initial test: Anorectal manometry and balloon expulsion test
Initial testing normal or inconclusive: Barium or MR defecography
Differential Diagnosis
Diabetes mellitus with autonomic neuropathy
Medications
Opioids (OIC)
Iron supplements