Urinary Retention and Incontinence

Retention

General

Etiology

  • Outflow obstruction

  • Neurologic

  • Iatrogenic: Medications commonly associated with retention include

    • Anticholinergics: Scopolamine, oxybutynin (bladder antispasmodic), dicyclomine (Bentyl), benztropine

    • Antihistamines: Diphenhydramine, hydroxyzine

    • Muscle relaxants: Cyclobenzaprine (Flexeril)

    • Neurologic/Psychiatric

      • Tricyclic antidepressants: Amitriptyline, nortriptyline

      • Antiparkinsonian: Amantadine, levodopa (Sinamet)

      • Antipsychotics: Haloperidol, chlorpromazine, fluphenazine (Prolixin), prochlorperazine (Compazine)

    • Hormonal: Estrogen, progesterone, testosterone

Incontinence

General Incontinence Interview

3 Question Incontinence.PNG
  • Perform 3 Question Incontinence Questionnaire

  • Rule out red flags including hematuria, obstructive symptoms, recurrent UTIs

  • Rule out reversible causes (DIAPPERS)

    • Delirium

    • Infection (acute UTI)

    • Atrophic vaginitis

    • Pharmaceuticals, e.g.

      • Antihistamine/anticholinergic (retention → overflow incontinence)

      • Antihypertensive: Diuretics, ACE inhibitors, Calcium channel blockers

      • Pain medications: COX-2 NSAIDs, muscle relaxants, opioids

    • Psychological disorder, especially depression

    • Excessive urine output (e.g. hyperglycemia)

    • Reduced mobility (i.e. functional incontinence)

    • Stool impaction (constipation → retention → overflow incontinence)

  • Explore effect of symptoms on patient’s quality of life

  • Review 3 day voiding diary

Differential Diagnosis